Health, Medical, Research, Science

Blood pressure study linked to dementia

MEDICAL RESEARCH

A major study suggests that hundreds of thousands of people could be saved from dementia if blood pressure tablets were used more widely.

Researchers have shown for the first time that aggressively treating high blood pressure – particularly in middle age – could also significantly reduce the risk of dementia later on.

NHS officials are under growing pressure to lower the threshold at which people can be given the drugs, a policy that could make 14million eligible for treatment.

Patients are currently considered to have hypertension – or high blood pressure – only if they have a reading of more than 140/90 mm Hg.

But a study of 9,400 people in the US found cutting the systolic threshold – the higher reading – to 120 instead of 140 slowed cognitive decline.

An ideal blood pressure reading is between 90/60 millimetres of mercury (mm Hg) and 120/80. The first figure is the systolic pressure, the “surge” that occurs with each heartbeat. The second is the diastolic reading, which measures the pressure in the “rest” between heartbeats.

Using the new threshold over eight years reduced rates of dementia and mild cognitive impairment by 15 per cent, according to results presented at the Alzheimer’s Association International Conference in Chicago.

Similar trials have shown cutting the threshold for treatment would reduce the risk of heart disease by a fifth, and strokes by about a quarter.

Health watchdogs are already reviewing blood pressure guidelines with a view to cutting rates of heart disease and a decision is expected next year.

But they will now face greater pressure to change the rules after the new research, the first to look in detail at the impact of such a policy on dementia.

Study leader Professor Jeff Williamson, of the Wake Forest School of Medicine in North Carolina, said: “These results support the need to maintain well-controlled blood pressure, especially for persons over 50.”

A second study of 670 patients by the University of Pennsylvania found that the lower threshold also showed shrinkage of white brain matter, strengthening the link between blood pressure and dementia.

The US has led the way on blood pressure policy, lowering the treatment threshold in November from a systolic score of 140 to 130.

If the UK followed suit, it would mean an estimated 14million people – a third of all adults – would be eligible. Currently seven million are eligible.

A policy to increase this, however, would be controversial as it would affect many people who until now have been considered healthy. A similar change that lowered the threshold for cholesterol-busting statin drugs in 2014 led to a huge backlash, fueling accusations that health professionals were “over-medicalising” the middle aged.

A spokesperson for Alzheimer’s Research UK, said: “This study suggests treating high blood pressure intensively . . . may help to reduce the risk of memory and thinking problems.

“There is robust evidence that what’s good for the heart is also good for the brain and maintaining good vascular health is one of the key things people can do to reduce their risk of dementia.”

But Professor Clive Ballard, of Exeter University, warned: “All anti-hypertensives come with some risk of adverse effects, most seriously for kidney function.”

 

THOSE who feel light-headed when standing up after a long time sitting may be at a greater risk of dementia and stroke, according to a US study of more than 11,000 people.

Scientists at John Hopkins University found those whose blood pressure dropped when they stood up – a problem known as orthostatic hypotension – had twice the risk of suffering a stroke in later life. Their risk of dementia was 54 per cent higher.

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Government, Legal, Scotland

Scotland’s EU Continuity Bill now being tested in Supreme Court

SCOTLAND: BREXIT

THE highest court in the UK has been urged to strike down the SNP’s Brexit legislation because it relates to international powers which are not devolved to Holyrood.

A legal battle between the Scottish and UK Governments is underway in the Supreme Court. It could have huge ramifications for Theresa May’s Brexit plans.

The UK’s top law officers argued that the SNP’s Continuity Bill, which has been passed by a majority of MSPs in the Scottish Parliament, “cannot stand” because it is “fundamentally inconsistent” with the law.

But the Scottish Government’s top legal officer insisted that the Bill was “carefully framed” not to cut across EU laws and was modelled on the UK Government’s Withdrawal Bill.

The case was called after the SNP opted to press ahead with its own Brexit legislation following its decision to refuse to give consent to Mrs May’s Bill.

The legislation was fast-tracked through parliament, despite Holyrood’s Presiding Officer Ken Macintosh concluding that it was “not within the legislative competence of the parliament”.

The Supreme Court is considering the issue after UK law officers asked for a judgment. The case is continuing, with a verdict expected in October.

Presenting the UK case, Advocate General for Scotland Lord Richard Keen told the seven judges considering the matter that “the Scottish Bill as a whole cannot stand”.

He told the panel, including Supreme Court president Lady Hale and deputy president Lord Reed, that the Bill “impermissibly modifies the UK Act on withdrawal from the EU” and is “fundamentally inconsistent” with legislation passed by MPs.

He argued that the Continuity Bill was “directly inconsistent with the UK Act at the most basic of levels” and that “the two simply cannot stand together”.

The UK law officers’ written case states: “The Scottish Bill is not law because it relates to the reserved matter of international relations as defined in Section 7 (1) of Schedule 5, and is therefore outside of competence.”

The UK Bill was given Royal Assent on June 26 and became the European Union (Withdrawal) Act 2018.

The law officers say that the Scottish Bill was passed “without knowledge” of the outcome of negotiations between the UK Government and the EU.

In his written case, Scottish Lord Advocate James Wolffe said: “The purpose of the Scottish Bill is to promote legal certainty by making provision for the continuity within the domestic legal system of existing EU-derived law upon and following withdrawal.”


HOLYROOD’S Brexit Bill is “perfectly practical”, the Lord Advocate told the UK Supreme Court as the Scottish Government continued its unprecedented constitutional battle with Whitehall.

In the second and final day of the court hearing in London, James Wolffe rejected the UK Government’s main contention that, by Passing Edinburgh’s Continuity Bill, the Scottish Parliament was in some way trying to cut across Westminster’s authority in international relations.

He argued that the Scottish bill was not incompatible with EU law, which was based on the principles of “legal certainty and continuity”.

The Lord Advocate said the Holyrood legislation only impacted on the “domestic legal order” and so could not affect the UK’s negotiations with Brussels.

Crucially, Mr Wolffe told the court the Scottish legislation had been passed by MSPs several months before the UK Government’s flagship EU Withdrawal Bill became law, noting: “It was not intended to modify the UK bill and could not do so.”

On the first day of the hearing, Lord Keen of Elie, Advocate General for Scotland, leading for the UK Government, argued that “any reasonable consideration” of the Scottish bill and the UK act showed the former sought to modify, that is undermine, the latter and so the “two simply cannot stand together” as they produced two “dual but inconsistent regimes” in respect of retained EU law.

But the Lord Advocate’s points were supported by Michael Fordham for the Welsh Government, who claimed the UK Government’s contention that the Scottish bill would cut across Whitehall’s reserved powers on international relations was “wrong and incoherent”.

He said the UK’s argument that devolved administrations could not legislate in devolved areas currently managed by the EU because they touched on international treaty negotiations was an “extravagant claim which has very alarming logical implications”.

He explained that this would have the effect of restricting the powers of devolved parliaments even after Brexit and EU law was transferred on to the UK Statute Book.

John Larkin, the Northern Irish Attorney General, also argued that the Scottish bill was “within the legislative competence of the Scottish Parliament”.

But, in response, Lord Keen suggested it was “unjustified” for devolved governments to expect that all devolved powers should be handed over after Britain left the EU because, when the devolution settlement was drawn up 20 years ago, no one could have predicted Brexit.

He said it was “not open to the Scottish Government and the Scottish Parliament to assume that no new legislative constraints” would be introduced because of Britain leaving the EU.

He claimed the Continuity Bill was “fundamentally inconsistent” with the purpose of the UK act and that the confusion over which Parliament had jurisdiction over which European regulations would result in the undermining of the UK Government’s Brexit strategy.

Seven judges of the Supreme Court, including two Scottish judges, will now spend the summer considering their ruling. If they were to find for the Scottish Government, then this would mean the Continuity Bill would receive royal assent and become law.

However, this would mean there would be two competing pieces of legislation on the statute book, which would likely result in the matter returning to the Supreme Court to determine which act took precedence.

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Google, Government, Islamic State, Research, Society, Technology

Jihadi propaganda still active on YouTube

RESEARCH STUDY BY CEP

A study has revealed that YouTube repeatedly fails to remove jihadist videos within two hours of them being posted – because of “staggering holes” in its monitoring.

It found that the Google-owned video sharing site missed its target for taking down Islamic State films in one in four cases.

Dozens of terrorist-propaganda and recruitment videos were left for public viewing for more than three days at a time, clocking up tens of thousands of views, according to the three-month study by the Counter Extremism Project (CEP).

Disturbing, too, is that six in ten of the IS supporters who posted the hate videos were not even banned from the site and their accounts remain active.

The failings come after YouTube rejected an offer of free technology to instantly block any previously identified extremist content, preferring to develop its own system that it says deletes millions of banned videos before they are seen.

At the G7 summit in October last year, YouTube joined with Facebook, Twitter and Microsoft in an accord aimed at removing extremist content from their platforms within two hours.

But in the first in-depth independent study of IS videos on YouTube, the CEP found this was not happening because of “inexcusable” holes in the service’s monitoring system. Researchers found 229 previously identified terror videos were uploaded 1,348 times and viewed on 163,000 occasions over three months from March 8 to June 8, with 24 per cent left on the site for more than two hours.

They included the film Caliphate 4 – uploaded six times during the trial period – in which a terrorist taunts former soldier Prince Harry.

Another video called Hunt Them O Monotheist was uploaded 12 times during the study and on one occasion allowed to remain for 39 hours.

Computer scientist Dr Hany Farid, from Dartmouth College in the US, who developed a system that stops child abuse films being uploaded, created a similar program that instantly identifies and removes terror videos.

YouTube, Facebook and Google were all offered the eGlyph system free by the CEP in 2016 but decided not to use it.

Dr Farid said it was “infuriating” that companies worth billions refused to implement systems that could instantly stop jihadist videos. “Spectacular failures are allowing terror groups to continue to radicalise and recruit online,” he added.

Former Conservative Party minister Mark Simmonds, now a senior adviser to CEP, said: “This study dispels any lingering myth that YouTube are doing enough to stop their site being used as an IS recruitment tool.

“The research shows that YouTube are not even meeting their own promise to delete all extremist content within two hours. For them to fail in a quarter of all cases, with much of the content still available three days or more after first being uploaded, is unacceptable.”

He added: “Even videos that stayed online for less than two hours received a total of nearly 15,000 hits – any one could become a potential terrorist.

“It is staggering and inexcusable that well over half of the IS supporters who upload this dangerous content are not even banned and their accounts remain active . . . spreading IS propaganda and grooming potential recruits.”

Google said it “rejects terrorism and has a strong track record of taking swift action against terrorist content”.

A spokesman added: “We’ve invested heavily in people and technology to ensure we keep making progress to detect and remove terror content as quickly as possible.

“We’re a founding member of the Global Internet Forum to Counter Terrorism, which sees tech companies collaborate to keep terror content off the web.”

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