Category Archives: Medical

Britain, Health, Medical, Research, Science

Findings suggest the use of pomegranate could halt Alzheimer’s…

MEDICAL RESEARCH

British scientists have said that pomegranates could help stop the progression of Alzheimer’s disease, a debilitating illness of the brain.

They claim a chemical compound in the fruit could prevent inflammation which destroys brain cells.

The findings raise hope that punicalagin could now be used in a drug to prevent or treat the condition, while the hunt for a cure continues. Treatments could also benefit sufferers of rheumatoid arthritis and Parkinson’s disease in the future, because any resulting drug could help to combat inflammation involved in these conditions too.

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Pomegranates have been used for centuries in Middle Eastern folk medicine and are said to be effective against heart disease, high blood pressure (hypertension), and some cancers, including prostate. The breakthrough shows that punicalagin can inhibit inflammation in specialised brain cells known as micrologia. This inflammation triggers the destruction of brain cells, which makes Alzheimer’s progressively worse.

Researchers at the University of Huddersfield along with colleagues at the University of Freiburg in Germany used brain cells from rats to test their findings.

Study leader Dr Olumayokun Olajide, of Huddersfield’s Department of Pharmacy, is now looking into how much pomegranate extract would be effective in a drug. He pointed out that juice products which are 100 per cent pomegranate contain approximately 3.4 per cent punicalagin. Most of the antioxidant compounds are found in the outer skin of the fruit.

Dr Olajide, added: ‘We do know that regular intake and regular consumption of pomegranate has a lot of health benefits – including prevention of neuro-inflammation related to dementia.’

Although the link has yet to be scientifically proven, pomegranate may be useful for treating inflammation in other conditions such as rheumatoid arthritis, Parkinson’s and cancer, not just neuro-inflammation of the brain.

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Government, Health, Medical, Research, Science, Society

Health risk for women in their 30s who do not exercise…

HEART RISK

A major study has found that a lack of exercise puts younger women at far greater risk of heart attacks than smoking or being obese.

Researchers found inactive women in their 30s are almost 50 per cent more likely to develop heart disease in their lifetime than those who are fit.

The team has now called on governments to launch public health campaigns on the importance of exercise, arguing it would have a far greater impact on reducing heart disease deaths than drives to discourage smoking or promote healthy eating.

The scientists looked at the records of 32,541 women aged 22 to 90, including details about lifestyle and whether they had heart disease. Armed with this data, they used a mathematical formula to work out their risk of heart disease during their lifetime based on whether they were inactive, were smokers, had hypertension (high blood pressure) or were obese.

A lack of exercise was found to pose the greatest risk to women across all age groups.

Those in their early 30s who were classed as inactive were nearly 50 per cent more likely to suffer from the condition in their lifetime than active women.

The risk decreased slightly with age. Inactive women in their late 40s were 38 per cent more at risk, falling to 28 per cent in the late 50s.

By comparison, the risk was 40 per cent for women smokers in their 30s and 30 per cent for the obese. Although obesity and being unfit are closely linked, the researchers from the University of Queensland pointed out that many slim women are inactive.

The latest UK figures show a quarter of women are classified as inactive, while just over half do the recommended two and a half hours of physical activity a week.

Heart disease, which includes heart attacks and strokes, is by far the biggest killer in Britain, claiming 82,000 lives a year.

Experts have previously claimed that exercising can halve the risk of getting the condition because it lowers the blood pressure, reduces cholesterol which blocks arteries, and improves circulation.

Professor Wendy Brown, one of the team’s lead researchers, described inactivity as the ‘Cinderella risk factor’ for heart disease. She said: ‘Our data suggests that national programmes for the promotion and maintenance of physical activity across the adult lifespan, but especially in young adulthood, deserve to be a much higher public health priority for women than they are now.’

The study’s findings, first published in the British Journal of Sports Medicine, concluded: ‘Continuing efforts to reduce smoking rates in young adult women are warranted… however, from about age 30, the population attributable risk for inactivity outweighs that of the other leading risk factors, including high Body Mass Index, which is currently receiving much more attention.’

A spokesperson for the British Heart Foundation, said: ‘We already know physical inactivity is a major risk factor for heart disease. Interestingly, this study shows its dominant influence on heart disease amongst women, and suggests a greater need to promote regular physical activity… It is important to remember that heart disease is linked to other factors such as smoking, obesity, high blood pressure and high cholesterol.’

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Government, Health, Medical, Research, Science, Scotland, Society

Scottish scientists in a breakthrough bid to find a vaccine for malaria…

MALARIA VACCINE

Scientists in Scotland trying to produce a vaccine for malaria have successfully tested a prototype on mice.

Researchers at Edinburgh University found that their vaccine enabled the immune system to produce antibodies which responded to the human malaria parasite.

Mosquito-borne malaria kills around 600,000 people around the world each year and many forms of the disease are becoming resistant to existing drugs.

A successful vaccine is difficult to produce as it must contain proteins which are present in the malaria parasite in order for the immune system to produce antibodies.

Malaria proteins, however, have a complex chemical structure, which is difficult to reproduce in a laboratory.

Despite that, scientists in Edinburgh have managed to grow them inside a tiny single-celled aquatic creature.

It’s hoped the technique will not only make a vaccine possible but easy to produce, as the creature can multiply quickly.

The team leader, Dr David Cavanagh, from the immunology department at Edinburgh University, said:

… There is a desperate need for an effective vaccine which can be made easily in large quantities.

He added:

… Our findings meet this challenge and, with more work, could lead to a vaccine to help those most at risk.

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